Reduction of deaths after drug labelling for risk of Reye's syndrome.

نویسنده

  • M Casteels-Van Daele
چکیده

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منابع مشابه

Reye's syndrome in the United States from 1981 through 1997.

BACKGROUND Reye's syndrome is characterized by encephalopathy and fatty degeneration of the liver, usually after influenza or varicella. Beginning in 1980, warnings were issued about the use of salicylates in children with those viral infections because of the risk of Reye's syndrome. METHODS To describe the pattern of Reye's syndrome in the United States, characteristics of the patients, and...

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Co-existence of hepatitis A and adult Reye's syndrome.

Reye's syndrome is most frequently seen in children but has also been described in adults. This syndrome is usually associated with ingestion of 5-aminosalicylates (ASA) or infection with influenza A, influenza B, or varicella virus. A case of Reye's syndrome in a 47 year old, previously healthy woman precipitated by ingestion of ASA and acute hepatitis A virus infection is described. Reye's sy...

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Clinical features and prognosis of Reye's syndrome.

Twenty three sporadic cases of Reye's syndrome diagnosed according to widely accepted criteria were seen between 1979 and 1982. The patients were younger than those reported from North America (median age 9 months), girls were twice as common as boys, and the syndrome presented twice as frequently in the summer 6 months. The annual incidence was 1.4 cases/100 000 among children aged less than 4...

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Public Health Service study of Reye's syndrome and medications. Report of the main study.

Between January 1985 and May 1986, following completion of a pilot study, a main study concerning the possible association between Reye's syndrome and salicylates was conducted. Twenty-seven patients with stage II or deeper Reye's syndrome whose diagnoses were confirmed by an expert panel and who had appropriate antecedent illnesses (chickenpox, respiratory illness, or gastrointestinal illness)...

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Reye's syndrome in the British Isles: first annual report of the joint British Paediatric Association and Communicable Disease Surveillance Centre surveillance scheme.

Reye's syndrome is a severe acute paediatric disorder characterised by encephalopathy with pronounced cerebral oedema and by diffuse fatty infiltration of the viscera, particularly the liver.' It may occur at any age in childhood. Typically a previously normal child has a viral type prodromal illness followed in a few days by vomiting, altered consciousness, and often convulsions. The liver may...

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عنوان ژورنال:
  • Lancet

دوره 341 8837  شماره 

صفحات  -

تاریخ انتشار 1992